High-Shear Homogenizers & Expert Services

Specializing in Biotechnology, Pharmaceuticals, Personal Care, Food/Beverage, and Cannabis.
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Introducing the all new ShearJet® HL60 V2
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Dyhydromatics, LLC designs and manufactures laboratory through production high pressure homogenizers used to reduce particles to the nano level. Our specially designed ShearJet® processors, assembled and tested in Maynard, Massachusetts, achieve a repeatable, evenly distributed, uniform particle down to the nano level that is unmatched. Unlike the competition, we are a full package company offering superior machines, parts, and services.

We are the masters when it comes to customer satisfaction.

Equipment

Homogenizer Equipment Laboratory Through Production Systems

Small Volume Homogenizer

ShearJet® HL60

Setting new standards in the high shear homogenizer industry!

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Medium Volume Homogenizers

ShearJet® PL300 & HP350 V2

Pneumatic laboratory benchtop and electric hydraulic high shear homogenizers

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Pilot Scale Homogenizer

ShearJet® HP1200 V2

Pilot and small production processors.

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Feed & Skid Systems

Working with our partner, we can design a complete turnkey system to reduce processing time, lower dead volumes, and increase product recovery.

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Our Services

Customer Service

Our exemplary customer service and support is second to none.

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Equipment Service & Consultation

Over 30 years of servicing all brands of high shear processors and lab equipment.

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Proof of Concept

We process your product with Dyhydromatics technology and provide a complimentary evaluation report of the results.

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Process Development

With experience in over 1500 formulations over the years, we can address even the most challenging applications to help you determine optimal process parameters for your formulation.

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News, Articles, & Case Studies

Dyhydromatics Exhibits at AAPS 2024 PHarmSCi 360
Dyhydromatics Exhibits at AAPS 2024 PHarmSCi 360

December 23, 2024

Our Technology
Our Technology

August 6, 2024

Vaccines and Vaccine Adjuvants
Vaccines and Vaccine Adjuvants

January 25, 2024

Cell disruption methodologies
Cell disruption methodologies

December 15, 2023

What is High-Shear Processing?
What is High-Shear Processing?

December 7, 2023

Nanoparticles in anesthesia
Nanoparticles in anesthesia

September 20, 2023

mRNA Technology and How High-Shear Processors Fit In
mRNA Technology and How High-Shear Processors Fit In

September 5, 2023

Solvent-free production methods for liposomes and lipid nanoparticles
Solvent-free production methods for liposomes and lipid nanoparticles

August 23, 2023

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Markets that Benefit from Our High Shear Processing.

Pharmaceutical
Consistent uniform particle size reduction (to nano sizes) allows the pharmaceutical industry to create far more stable products with targeted delivery.

Biotechnology
Gentle, productive cell disruption is vital to the biotech industry to study and use the intercellular materials. Demand for these materials is on the increase as they are used in other industries as well, including pharmaceutical, agriculture, and bio-services.

Chemical
Exemplary nanoemulsions, liposomes, and biochemical cell disruption within the chemical industry lead to products with longer shelf-life and stable formulations.

Personal Care / Cosmeceuticals
Nanotechnology allows cosmetics to deliver benefits to a targeted depth, and to eliminate unwanted side affects, like the white coating in sunscreen.

Food / Nutraceuticals
Much advancement has come to fruition in the past decade incorporating nanoemulsions, nanodispersions and encapsulation in the food and beverage industries. These have allowed for targeted delivery of bioactives, longer shelf life, enhanced flavor/aroma, and improved mouth-feel with fat reduction.

Cannabis
While cannabis nanoparticle research is in its infancy, high shear processing is a superior method of increasing bioavailability, and achieving stable formulations.

What They're Saying About Dyhydromatics

Mecozzi Lab Employees
University of Wisconsin-Madison

The best part of working with Dyhydromatics is their customer service. The employees not only have a broad, technical knowledge base but they are also easy to reach over the phone or email and provide unprecedented assistance.

Nelson Landrau
Laundrau Scientific Innovations

I find the ShearJet processor to work more efficiently than the competitive fixed-geometry processor because I can process more material in less time. What took me 3 passes before, I can achieve in one pass on the ShearJet processor.

J. Kendall Killgore
Director, Product Development
Kereos, Inc.

Fortunately for our company, that’s where Dyhydromatics came in. T Field Service Technician did everything – in just a few hours he carried out a complete preventive maintenance on our purchase and then took the time to instruct me on its operation.